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Summer 2007 Traveling with Asthma and Allergies AARC Diagnosis and Treatment of Asthma in Elderly Patients Smoking and the Asthma Patient
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Smoking and the Asthma Patient The RT’s challenge: educate the 25% of adults with asthma who also smoke. Don't smoke! Everyone knows it's bad for you, but respiratory
therapists still encounter many asthma patients who smoke or expose
their loved ones to dangerous second-hand smoke. This article, appearing
in AARC Times, while containing some medical terminology, may alert
you to the importance of tobacco avoidance as an asthma sufferer. In my early years in respiratory therapy it never occurred to me how self-inflicted triggers were so significant in patients with asthma. I had assumed that most smokers did not already have a chronic lung disease—because they certainly would not want to damage their lungs any more than they already were. Right? Wrong! I soon found out that nothing could be further from the truth. More to the point, cigarette smoking (whether it is firsthand or secondhand) is dangerous for all people but is even more so for those with asthma. Secondhand smoke inhalation presents its own reason for us to be concerned for patients with asthma. There is nothing more disheartening than to see a car with children in the back seat while adults are smoking cigarettes in the front seat. It doesn’t matter whether the child has asthma or not. Of course, in this situation the child with asthma is forced to endure a potentially deadly trigger. Living in self-denial The first place a patient with asthma will go to if an exacerbation cannot be managed at home will be to the local emergency department. A recent multi-center study by Silverman et al noted that in 64 emergency departments 35% of asthmatic admissions were acknowledged smokers. Astoundingly, 50% of them stated they understood that smoking worsened their condition but smoked anyway.3 This is incredible self-denial. Making matters worse Smoking cigarettes may actually modify the inflammatory process to the point that there may be corticosteroid resistance, which ultimately will interfere with the very medications that serve to prevent symptoms of the disease.4 This interaction is just now being understood, and it is speculated that it could be due to alterations in airway inflammatory cell phenotypes, changes in glucocorticoid receptor alpha to beta ratio, and reduced histone deacetylase activity. Smoking also can increase the clearance of drugs such as theophylline by induction of metabolizing enzymes.5 The symptoms that smokers with asthma exhibit are realized with daily respiratory sequela, primarily that of sputum production with nocturnal shortness of breath and wheezing.6 As we learn more about this relationship, there may be a need to evaluate other means of inflammatory control. But the best remedy is to stop smoking. Smoking cessation may actually serve to restore corticosteroid responsiveness in asthmatic ex-smokers. Particularly troubling is the teenage smoker with asthma. Making it even more of a challenge is the fact that this is a difficult age group to influence. Studies have shown that it may be easier for teenaged girls (as compared to boys) to quit smoking as they are often more concerned with image and appearance. In large part, there needs to be a motivating factor.7 Of particular concern is that this is also the age when most lifelong smokers start their habit: teenagers’ smoking initiation starts early. A study by Robinson et al found that initial smoking occurred at a mean age of less then 12 years and daily smoking at age 13 years.8 The reasons for starting were the same whether or not the child had asthma. This is an age group that is in need of targeted smoking-cessation intervention. Motivating our patients References
Smoking may actually modify the inflammatory process and cause corticosteroid resistance, which ultimately will interfere with the medications that prevent disease symptoms. About the Author |
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